Aloy P, Bottcher B, Ceulemans H, Leutwein C, Mellwig C, Fischer S, Gavin AC, Bork P, Superti-Furga G, Serrano L, Russell RB: Structure-based assembly of protein complexes in yeast. Science. 2004, 303 (5666): 2026-2029. 10.1126/science.1092645
Article
CAS
PubMed
Google Scholar
Bork P, Serrano L: Towards cellular systems in 4D. Cell. 2005, 121 (4): 507-509. 10.1016/j.cell.2005.05.001
Article
CAS
PubMed
Google Scholar
Gavin AC, Aloy P, Grandi P, Krause R, Boesche M, Marzioch M, Rau C, Jensen LJ, Bastuck S, Dumpelfeld B, Edelmann A, Heurtier MA, Hoffman V, Hoefert C, Klein K, Hudak M, Michon AM, Schelder M, Schirle M, Remor M, Rudi T, Hooper S, Bauer A, Bouwmeester T, Casari G, Drewes G, Neubauer G, Rick JM, Kuster B, Bork P, Russell RB, Superti-Furga G: Proteome survey reveals modularity of the yeast cell machinery. Nature. 2006, 440 (7084): 631-636. 10.1038/nature04532
Article
CAS
PubMed
Google Scholar
Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrin-Alvarez JM, Shales M, Zhang X, Davey M, Robinson MD, Paccanaro A, Bray JE, Sheung A, Beattie B, Richards DP, Canadien V, Lalev A, Mena F, Wong P, Starostine A, Canete MM, Vlasblom J, Wu S, Orsi C, Collins SR, Chandran S, Haw R, Rilstone JJ, Gandi K, Thompson NJ, Musso G, St Onge P, Ghanny S, Lam MH, Butland G, Altaf-Ul AM, Kanaya S, Shilatifard A, O'Shea E, Weissman JS, Ingles CJ, Hughes TR, Parkinson J, Gerstein M, Wodak SJ, Emili A, Greenblatt JF: Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 2006, 440 (7084): 637-643. 10.1038/nature04670
Article
CAS
PubMed
Google Scholar
Gunsalus KC, Ge H, Schetter AJ, Goldberg DS, Han JD, Hao T, Berriz GF, Bertin N, Huang J, Chuang LS, Li N, Mani R, Hyman AA, Sonnichsen B, Echeverri CJ, Roth FP, Vidal M, Piano F: Predictive models of molecular machines involved in Caenorhabditis elegans early embryogenesis. Nature. 2005, 436 (7052): 861-865. 10.1038/nature03876
Article
CAS
PubMed
Google Scholar
Bray D: Protein molecules as computational elements in living cells. Nature. 1995, 376 (6538): 307-312. 10.1038/376307a0
Article
CAS
PubMed
Google Scholar
Maciag K, Altschuler SJ, Slack MD, Krogan NJ, Emili A, Greenblatt JF, Maniatis T, Wu LF: Systems-level analyses identify extensive coupling among gene expression machines. Mol Syst Biol. 2006, 2: 2006 0003- 10.1038/msb4100045
Article
PubMed Central
PubMed
Google Scholar
Hart GT, Lee I, Marcotte ER: A high-accuracy consensus map of yeast protein complexes reveals modular nature of gene essentiality. BMC Bioinformatics. 2007, 8: 236- 10.1186/1471-2105-8-236
Article
PubMed Central
PubMed
Google Scholar
Deutschbauer AM, Jaramillo DF, Proctor M, Kumm J, Hillenmeyer ME, Davis RW, Nislow C, Giaever G: Mechanisms of haploinsufficiency revealed by genome-wide profiling in yeast. Genetics. 2005, 169 (4): 1915-1925. 10.1534/genetics.104.036871
Article
PubMed Central
CAS
PubMed
Google Scholar
Giaever G, Chu AM, Ni L, Connelly C, Riles L, Veronneau S, Dow S, Lucau-Danila A, Anderson K, Andre B, Arkin AP, Astromoff A, El-Bakkoury M, Bangham R, Benito R, Brachat S, Campanaro S, Curtiss M, Davis K, Deutschbauer A, Entian KD, Flaherty P, Foury F, Garfinkel DJ, Gerstein M, Gotte D, Guldener U, Hegemann JH, Hempel S, Herman Z, Jaramillo DF, Kelly DE, Kelly SL, Kotter P, LaBonte D, Lamb DC, Lan N, Liang H, Liao H, Liu L, Luo C, Lussier M, Mao R, Menard P, Ooi SL, Revuelta JL, Roberts CJ, Rose M, Ross-Macdonald P, Scherens B, Schimmack G, Shafer B, Shoemaker DD, Sookhai-Mahadeo S, Storms RK, Strathern JN, Valle G, Voet M, Volckaert G, Wang CY, Ward TR, Wilhelmy J, Winzeler EA, Yang Y, Yen G, Youngman E, Yu K, Bussey H, Boeke JD, Snyder M, Philippsen P, Davis RW, Johnston M: Functional profiling of the Saccharomyces cerevisiae genome. Nature. 2002, 418 (6896): 387-391. 10.1038/nature00935
Article
CAS
PubMed
Google Scholar
Sopko R, Huang D, Preston N, Chua G, Papp B, Kafadar K, Snyder M, Oliver SG, Cyert M, Hughes TR, Boone C, Andrews B: Mapping pathways and phenotypes by systematic gene overexpression. Mol Cell. 2006, 21 (3): 319-330. 10.1016/j.molcel.2005.12.011
Article
CAS
PubMed
Google Scholar
Spellman PT, Sherlock G, Zhang MQ, Iyer VR, Anders K, Eisen MB, Brown PO, Botstein D, Futcher B: Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridization. Mol Biol Cell. 1998, 9 (12): 3273-3297.
Article
PubMed Central
CAS
PubMed
Google Scholar
Bray D, Lay S: Computer-based analysis of the binding steps in protein complex formation. Proc Natl Acad Sci U S A. 1997, 94 (25): 13493-13498. 10.1073/pnas.94.25.13493
Article
PubMed Central
CAS
PubMed
Google Scholar
Veitia RA: Exploring the etiology of haploinsufficiency. Bioessays. 2002, 24 (2): 175-184. 10.1002/bies.10023
Article
CAS
PubMed
Google Scholar
Papp B, Pal C, Hurst LD: Dosage sensitivity and the evolution of gene families in yeast. Nature. 2003, 424 (6945): 194-197. 10.1038/nature01771
Article
CAS
PubMed
Google Scholar
de Lichtenberg U, Jensen LJ, Brunak S, Bork P: Dynamic complex formation during the yeast cell cycle. Science. 2005, 307 (5710): 724-727. 10.1126/science.1105103
Article
CAS
PubMed
Google Scholar
Pereira-Leal JB, Levy ED, Kamp C, Teichmann SA: Evolution of protein complexes by duplication of homomeric interactions. Genome Biol. 2007, 8 (4): R51- 10.1186/gb-2007-8-4-r51
Article
PubMed Central
PubMed
Google Scholar
Stranger BE, Dermitzakis ET: From DNA to RNA to disease and back: the 'central dogma' of regulatory disease variation. Hum Genomics. 2006, 2 (6): 383-390.
Article
PubMed Central
CAS
PubMed
Google Scholar
Beckmann JS, Estivill X, Antonarakis SE: Copy number variants and genetic traits: closer to the resolution of phenotypic to genotypic variability. Nat Rev Genet. 2007, 8 (8): 639-646. 10.1038/nrg2149
Article
CAS
PubMed
Google Scholar
Lehner B, Fraser AG: A first-draft human protein-interaction map. Genome Biol. 2004, 5 (9): R63- 10.1186/gb-2004-5-9-r63
Article
PubMed Central
PubMed
Google Scholar
Franke L, Bakel H, Fokkens L, de Jong ED, Egmont-Petersen M, Wijmenga C: Reconstruction of a functional human gene network, with an application for prioritizing positional candidate genes. Am J Hum Genet. 2006, 78 (6): 1011-1025. 10.1086/504300
Article
PubMed Central
CAS
PubMed
Google Scholar
Lage K, Karlberg EO, Storling ZM, Olason PI, Pedersen AG, Rigina O, Hinsby AM, Tumer Z, Pociot F, Tommerup N, Moreau Y, Brunak S: A human phenome-interactome network of protein complexes implicated in genetic disorders. Nat Biotechnol. 2007, 25 (3): 309-316. 10.1038/nbt1295
Article
CAS
PubMed
Google Scholar
Mewes HW, Frishman D, Mayer KF, Munsterkotter M, Noubibou O, Pagel P, Rattei T, Oesterheld M, Ruepp A, Stumpflen V: MIPS: analysis and annotation of proteins from whole genomes in 2005. Nucleic Acids Res. 2006, 34 (Database issue): D169-72. 10.1093/nar/gkj148
Article
PubMed Central
CAS
PubMed
Google Scholar
Benjamini Y, Hochberg Y: Controlling the false discovery rate: a practical and powerful approach to multiple testing. Journal of the Royal Statistical Society Series B (Methodological). 1995, 57 (1): 289-300.
Google Scholar