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Volume 13 Supplement 2

Selected articles from the 17th Asia Pacific Bioinformatics Conference (APBC 2019): systems biology


Publication of this supplement has not been supported by sponsorship. Information about the source of funding for publication charges can be found in the individual articles. The articles have undergone the journal's standard peer review process for supplements. The Supplement Editors declare that they have no competing interests.

Wuhan, China14-16 January 2019

Edited by David Sankoff, Guoliang Li, Louxin Zhang, Yi-Ping Phoebe Chen, Shaoliang Peng and Hong-Yu Zhang

Conference website

  1. Major alteration in lifestyle of human population has promoted Type 2 diabetes mellitus (T2DM) to the level of an epidemic. This metabolic disorder is characterized by insulin resistance and pancreatic β-cell dys...

    Authors: Pritha Dutta, Lichun Ma, Yusuf Ali, Peter M.A. Sloot and Jie Zheng
    Citation: BMC Systems Biology 2019 13(Suppl 2):36
  2. Identification of Hürthle cell cancers by non-operative fine-needle aspiration biopsy (FNAB) of thyroid nodules is challenging. Resultingly, non-cancerous Hürthle lesions were conventionally distinguished from...

    Authors: Yangyang Hao, Quan-Yang Duh, Richard T. Kloos, Joshua Babiarz, R. Mack Harrell, S. Thomas Traweek, Su Yeon Kim, Grazyna Fedorowicz, P. Sean Walsh, Peter M. Sadow, Jing Huang and Giulia C. Kennedy
    Citation: BMC Systems Biology 2019 13(Suppl 2):27
  3. Biological experiments have confirmed the association between miRNAs and various diseases. However, such experiments are costly and time consuming. Computational methods help select potential disease-related m...

    Authors: Xiaoying Li, Yaping Lin, Changlong Gu and Jialiang Yang
    Citation: BMC Systems Biology 2019 13(Suppl 2):26
  4. Anti-tumor necrosis factor alpha (TNF- α) therapy has made a significant impact on treating psoriasis. Despite these agents being designed to block TNF- α activity, their mechanism of action in the remission of p...

    Authors: Lunfei Liu, Wenting Liu, Yuxin Zheng, Jisu Chen, Jiong Zhou, Huatuo Dai, Suiqing Cai, Jianjun Liu, Min Zheng and Yunqing Ren
    Citation: BMC Systems Biology 2019 13(Suppl 2):29
  5. Single-cell RNA sequencing (scRNAseq) data always involves various unwanted variables, which would be able to mask the true signal to identify cell-types. More efficient way of dealing with this issue is to ex...

    Authors: Shiquan Sun, Yabo Chen, Yang Liu and Xuequn Shang
    Citation: BMC Systems Biology 2019 13(Suppl 2):28