Van der Werf MJ, Guettler MV, Jain MK, Zeikus JG. Environmental and physiological factors affecting the succinate product ratio during carbohydrate fermentation by Actinobacillus sp. 130Z. Arch Microbiol. 1997;167:332–42.
Liu YP, Zheng P, Sun ZH, Ni Y, Dong JJ, Zhu LL. Economical succinic acid production from cane molasses by Actinobacillus succinogenes. Bioresour Technol. 2008;99:1736–42.
Urbance SE, Pometto AL, DiSpirito A a., Denli Y: Evaluation of succinic acid continuous and repeat-batch biofilm fermentation by Actinobacillus succinogenes using plastic composite support bioreactors. Appl Microbiol Biotechnol 2004, 65:664–670.
Guettler MV, Rumler D, Jainf MK. Actinobacillus succinogenes sp. nov., a novel succinic-acid-producing strain from the bovine rumen. Int J Syst Bacteriol. 1999;49(1 999):207–16.
Gunnarsson IB, Alvarado-morales M, Angelidaki I. Utilization of CO2 fixating bacterium Actinobacillus succinogenes 130Z for simultaneous biogas upgrading and biosuccinic acid production. Environ Sci Technol. 2014;48:12464–8.
Shen N, Qin Y, Wang Q, Liao S, Zhu J, Zhu Q, Mi H, Adhikari B, Wei Y, Huang R. Production of succinic acid from sugarcane molasses supplemented with a mixture of corn steep liquor powder and peanut meal as nitrogen sources by Actinobacillus succinogenes. Lett Appl Microbiol. 2015;60:544–51.
Zheng P, Dong JJ, Sun ZH, Ni Y, Fang L. Fermentative production of succinic acid from straw hydrolysate by Actinobacillus succinogenes. Bioresour Technol. 2009;100:2425–9.
Wan C, Li Y, Shahbazi A, Xiu S. Succinic acid production from cheese whey using Actinobacillus succinogenes 130 Z. Appl Biochem Biotechnol. 2008;145:111–9.
Chen K, Jiang M, Wei P, Yao J, Wu H. Succinic acid production from acid hydrolysate of corn fiber by Actinobacillus succinogenes. Appl Biochem Biotechnol. 2010;160:477–85.
Jiang M, Chen K, Liu Z, Wei P, Ying H, Chang H. Succinic acid production by Actinobacillus succinogenes using spent brewer’s yeast hydrolysate as a nitrogen source. Appl Biochem Biotechnol. 2010;160:244–54.
Xi YL, Chen KQ, Dai WY, Ma JF, Zhang M, Jiang M, Wei P, Ouyang PK. Succinic acid production by Actinobacillus succinogenes NJ113 using corn steep liquor powder as nitrogen source. Bioresour Technol. 2013;136:775–9.
Li Q, Yang M, Wang D, Li W, Wu Y, Zhang Y, Xing J, Su Z. Efficient conversion of crop stalk wastes into succinic acid production by Actinobacillus succinogenes. Bioresour Technol. 2010;101:3292–4.
Chen K, Zhang H, Miao Y, Jiang M, Chen J. Succinic acid production from enzymatic hydrolysate of sake lees using Actinobacillus succinogenes 130Z. Enzym Microb Technol. 2010;47:236–40.
Chen KQ, Li J, Ma JF, Jiang M, Wei P, Liu ZM, Ying HJ. Succinic acid production by Actinobacillus succinogenes using hydrolysates of spent yeast cells and corn fiber. Bioresour Technol. 2011;102:1704–8.
Yu J, Li Z, Ye Q, Yang Y, Chen S. Development of succinic acid production from corncob hydrolysate by Actinobacillus succinogenes. J Ind Microbiol Biotechnol. 2010;37:1033–40.
Zeikus JG, Jain MK, Elankovan P. Biotechnology of succinic acid production and markets for derived industrial products. Appl Microbiol Biotechnol. 1999;51:545–52.
Kamzolova SV, Vinokurova NG, Shemshura ON, Bekmakhanova NE, Lunina JN, Samoilenko VA, Morgunov IG. The production of succinic acid by yeast Yarrowia lipolytica through a two-step process. Appl Microbiol Biotechnol. 2014;98:7959–69.
Raab AM, Gebhardt G, Bolotina N, Weuster-Botz D, Lang C. Metabolic engineering of Saccharomyces cerevisiae for the biotechnological production of succinic acid. Metab Eng. 2010;12:518–25.
Yan D, Wang C, Zhou J, Liu Y, Yang M, Xing J. Construction of reductive pathway in Saccharomyces cerevisiae for effective succinic acid fermentation at low pH value. Bioresour Technol. 2014;156:232–9.
Liu Y, Wu H, Li Q, Tang X, Li Z, Ye Q. Process development of succinic acid production by Escherichia coli NZN111 using acetate as an aerobic carbon source. Enzym Microb Technol. 2011;49:459–64.
Scholten E, Renz T, Thomas J. Continuous cultivation approach for fermentative succinic acid production from crude glycerol by Basfia succiniciproducens DD1. Biotechnol Lett. 2009;31:1947–51.
Kim DY, Yim SC, Lee PC, Lee WG, Lee SY, Chang HN. Batch and continuous fermentation of succinic acid from wood hydrolysate by Mannheimia succiniciproducens MBEL55E. In Enzyme Microb Technol Volume. 2004;35:648–53.
Lee SY, Kim JM, Song H, Lee JW, Kim TY, Jang Y-S. From genome sequence to integrated bioprocess for succinic acid production by Mannheimia succiniciproducens. Appl Microbiol Biotechnol. 2008;79:11–22.
Cok B, Tsiropoulos I, Roes AL, Patel MK. Succinic acid production derived from carbohydrates: an energy and greenhouse gas assessment of a platform chemical toward a bio-based economy. Biofuels Bioprod Biorefin. 2014;8:16–29.
Choi S, Song CW, Shin JH, Lee SY. Biorefineries for the production of top building block chemicals and their derivatives. Metab Eng. 2015:223–39.
Jansen MLA, van Gulik WM. Towards large scale fermentative production of succinic acid. Curr Opin Biotechnol. 2014;30:190–7.
Lee SJ, Song H, Lee SY. Genome-based metabolic engineering of Mannheimia succiniciproducens for succinic acid production. Appl Environ Microbiol. 2006;72:1939–48.
Yan Q, Zheng P, Dong JJ, Sun ZH. A fibrous bed bioreactor to improve the productivity of succinic acid by Actinobacillus succinogenes. J Chem Technol Biotechnol. 2014;89:1760–6.
McKinlay JB, Zeikus JG, Vieille C. Insights into Actinobacillus succinogenes fermentative metabolism in a chemically defined growth medium. Appl Environ Microbiol. 2005;71:6651–6.
McKinlay JB, Vieille C. 13C-metabolic flux analysis of Actinobacillus succinogenes fermentative metabolism at different NaHCO3 and H2 concentrations. Metab Eng. 2008;10:55–68.
Li J, Jiang M, Chen K-QQ, Ye Q, Shang L-AA, Wei P, Ying H-JJ, Chang H-NN. Effect of redox potential regulation on succinic acid production by Actinobacillus succinogenes. Bioprocess Biosyst Eng. 2010;33:911–20.
Carvalho M, Matos M, Roca C, Reis M a M. Succinic acid production from glycerol by Actinobacillus succinogenes using dimethylsulfoxide as electron acceptor. New Biotechnol. 2014;31:133–9.
van Heerden CD, Nicol W. Continuous succinic acid fermentation by Actinobacillus succinogenes. Biochem Eng J. 2013;73:5–11.
Otero JM, Cimini D, Patil KR, Poulsen SG, Olsson L, Nielsen J. Industrial systems biology of Saccharomyces cerevisiae enables novel succinic acid cell factory. PLoS One. 2013;8
Sajo Mienda B, Shahir Shamsir M. Model-driven in silico glpC gene knockout predicts increased succinate production from glycerol in Escherichia coli. AIMS Bioeng. 2015;2:40–8.
Xu G, Zou W, Chen X, Xu N, Liu L, Chen J. Fumaric acid production in Saccharomyces cerevisiae by in silico aided metabolic engineering. PLoS One. 2012;7
Raab AM, Lang C. Oxidative versus reductive succinic acid production in the yeast Saccharomyces cerevisiae. Bioeng Bugs. 2011;2
Cheng KK, Wang GY, Zeng J, Zhang JA. Improved succinate production by metabolic engineering. Biomed Res Int. 2013;2013
Lin H, Bennett GN, San KY. Fed-batch culture of a metabolically engineered Escherichia coli strain designed for high-level succinate production and yield under aerobic conditions. Biotechnol Bioeng. 2005;90:775–9.
Liu R, Liang L, Chen K, Ma J, Jiang M, Wei P, Ouyang P. Fermentation of xylose to succinate by enhancement of ATP supply in metabolically engineered Escherichia coli. Appl Microbiol Biotechnol. 2012;94:959–68.
Zhang X, Jantama K, Moore JC, Jarboe LR, Shanmugam KT, Ingram LO. Metabolic evolution of energy-conserving pathways for succinate production in Escherichia coli. Proc Natl Acad Sci U S A. 2009;106:20180–5.
ya LL, ming LR, feng MJ, quan CK, Jiang M, Wei P. Increased production of succinic acid in Escherichia coli by overexpression of malate dehydrogenase. Biotechnol Lett. 2011;33:2439–44.
Yang J, Wang Z, Zhu N, Wang B, Chen T, Zhao X. Metabolic engineering of Escherichia coli and in silico comparing of carboxylation pathways for high succinate productivity under aerobic conditions. Microbiol Res. 2014;169:432–40.
Jiang M, Ma J, Wu M, Liu R, Liang L, Xin F, Zhang W, Jia H, Dong W. Progress of succinic acid production from renewable resources: metabolic and fermentative strategies. Bioresour Technol. 2017;
Zou W, Zhu L-W, Li H-M, Tang Y-J. Significance of CO2 donor on the production of succinic acid by Actinobacillus succinogenes ATCC 55618. Microb Cell Factories. 2011;10:87.
Xi Y, Chen K, Li J, Fang X, Zheng X, Sui S, Jiang M, Wei P. Optimization of culture conditions in CO2 fixation for succinic acid production using Actinobacillus succinogenes. J Ind Microbiol Biotechnol. 2011;38:1605–12.
McKinlay JB, Laivenieks M, Schindler BD, McKinlay A a, Siddaramappa S, Challacombe JF, Lowry SR, Clum A, Lapidus AL, Burkhart KB, Harkins V, Vieille C. A genomic perspective on the potential of Actinobacillus succinogenes for industrial succinate production. BMC Genomics 2010, 11:680.
McKinlay JB, Shachar-Hill Y, Zeikus JG, Vieille C. Determining Actinobacillus succinogenes metabolic pathways and fluxes by NMR and GC-MS analyses of 13C-labeled metabolic product isotopomers. Metab Eng. 2007;9:177–92.
Altschul SF, Gish W, Miller W, Myers EW, Lipman DJ. Basic local alignment search tool. J Mol Biol. 1990;215(3):403–10.
Eddy SR. Profile hidden Markov models. Bioinformatics. 1998;14(9):755–63.
The UniProt Consortium. UniProt: the universal protein knowledgebase. Nucleic Acids Res. 2018;46(5):2699.
Dias O, Rocha M, Ferreira EC, Rocha I. Reconstructing genome-scale metabolic models with merlin. Nucleic Acids Research. 2015;43(8):3899–910.
Kanehisa M, Goto S. KEGG: Kyoto Encyclopaedia of genes and genomes. Nucl Acids Res. 2000;28:27–30.
Saier MH, Reddy VS, Tamang DG, Västermark Å. The transporter classification database. Nucleic Acids Res. 2014;42
Caspi R, Billington R, Ferrer L, Foerster H, Fulcher CA, Keseler IM, Kothari A, Krummenacker M, Latendresse M, Mueller LA, Ong Q, Paley S, Subhraveti P, Weaver DS, Karp PD. The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases. Nucleic Acids Res. 2016;44:D471–80.
Flamholz A, Noor E, Bar-even A, Milo R. EQuilibrator - the biochemical thermodynamics calculator. Nucleic Acids Res. 2012;40
Santos S, Rocha I. A computation tool for the estimation of biomass composition from genomic and transcriptomic information. Adv. Intell. Syst. Comput. 2016:161–9.
Juty N, Ali R, Glont M, Keating S, Rodriguez N, Swat MJ, Wimalaratne SM, Hermjakob H, Le Novère N, Laibe C, Chelliah V. BioModels: content, features, functionality, and use. CPT Pharmacometrics Syst Pharmacol. 2015:55–68.
Rocha I, Maia P, Evangelista P, Vilaça P, Soares S, Pinto JP, Nielsen J, Patil KR, Ferreira EC, Rocha M. OptFlux: an open-source software platform for in silico metabolic engineering. BMC Syst Biol. 2010;4:45.
Bradfield MFA, Nicol W. Continuous succinic acid production from xylose by Actinobacillus succinogenes. Bioprocess Biosyst Eng. 2016;39:233–44.
Li J, Jiang M, Chen K, Shang L, Wei P, Ying H, Ye Q, Ouyang P, Chang H. Enhanced production of succinic acid by Actinobacillus succinogenes with reductive carbon source. Process Biochem. 2010;45:980–5.
Schindler BD, Joshi RV, Vieille C. Respiratory glycerol metabolism of Actinobacillus succinogenes 130Z for succinate production. J Ind Microbiol Biotechnol. 2014;41:1339–52.
Lin SKC, Du C, Koutinas A, Wang R, Webb C. Substrate and product inhibition kinetics in succinic acid production by Actinobacillus succinogenes. Biochem Eng J. 2008;41:128–35.
Orth JD, Conrad TM, Na J, Lerman JA, Nam H, Feist AM, Palsson BØ. A comprehensive genome-scale reconstruction of Escherichia coli metabolism—2011. Mol Syst Biol. 2011;
Mo ML, Palsson BO, Herrgård MJ. Connecting extracellular metabolomic measurements to intracellular flux states in yeast. BMC Syst Biol. 2009;3:37.
Pateraki C, Patsalou M, Vlysidis A, Kopsahelis N, Webb C, Koutinas AA, Koutinas M. Actinobacillus succinogenes: advances on succinic acid production and prospects for development of integrated biorefineries. Biochem Eng J. 2016;112:285–303.
Guarnieri MT, Chou YC, Salvachúa D, Mohagheghi A, St. John PC, Peterson DJ, Bomble YJ, Beckham GT. Metabolic engineering of Actinobacillus succinogenes provides insights into succinic acid biosynthesis. Appl Environ Microbiol. 2017;83
Song H, Lee JW, Choi S, You JK, Hong WH, Lee SY. Effects of dissolved CO2 levels on the growth of Mannheimia succiniciproducens and succinic acid production. Biotechnol Bioeng. 2007;98:1296–304.
Brink HG, Nicol W. Succinic acid production with Actinobacillus succinogenes: rate and yield analysis of chemostat and biofilm cultures. Microb Cell Factories. 2014;13:111.
Lin H, Bennett GN, San KY. Metabolic engineering of aerobic succinate production systems in Escherichia coli to improve process productivity and achieve the maximum theoretical succinate yield. Metab Eng. 2005;7:116–27.