In microbial production of non-catabolic products such as antibiotics a loss of production capacity upon long-term cultivation (for example chemostat), a phenomenon called strain degeneration, is often observe...
Authors:
Rutger D Douma, Joana M Batista, Kai M Touw, Jan AKW Kiel, Arjen M Krikken, Zheng Zhao, Tânia Veiga, Paul Klaassen, Roel AL Bovenberg, Jean-Marc Daran, Joseph J Heijnen and Walter M van Gulik
Citation:
BMC Systems Biology
2011
5:132
Content type: Research article
Published on: 19 August 2011